As global aging intensifies, the incidence of age-related bone metabolic disorders, such as osteoporosis, continues to climb.Seeking safe and effective therapeutic interventions is of utmost importance.The modulation of bone metabolism by the gut microbiota and their metabolites has emerged as a Licorice focal area of research.Short-chain fatty aci
MEK inhibition prevents CAR-T cell exhaustion and differentiation via downregulation of c-Fos and JunB
Abstract Clinical evidence supports the notion that T cell exhaustion and terminal differentiation pose challenges to the persistence and effectiveness of chimeric antigen receptor-T (CAR-T) cells.MEK1/2 inhibitors (MEKIs), widely used in cancer treatment due Concealer to their ability to inhibit aberrant MAPK signaling, have shown potential synerg
Fundamental length scale and the bending of light in a gravitational field
Abstract The canonical approach to quantizing quantum gravity is understood to suffer from pathological non-renomalizability.Nevertheless in the context of effective field theory, a viable perturbative approach to calculating elementary processes is possible.Some non-perturbative approaches, most notably loop quantum gravity and Priority Processing
Optimal Power Allocation and Delay Minimization Based on Conflict Graph Algorithm for Device-to-Device Communications
Device-to-device (D2D) technology is a promising technique in terms of being capable of providing efficiency, decreased latency, improved data rate, and increased capacity to cellular networks.Allocating power to users in order to reduce energy consumption and maintain quality of service (QoS) remains a major challenge in D2D communications.In this